Table 6: Pharmacokinetic parameters of valsartan after oral administration of the pure powder, marketed formulation (Valzaar), and liquid and solid SMEF.

ParametersPure drugValzaarL-SMEFS-SMSDS-SMFD

(μg/mL)
(h)
(h)
Kel (h−1)
AUC t 12 (μg h/mL)
AUC t  (μg h/mL)
2.93.02.98
1.61.681.62

: Relative bioavailability compared to pure drug.
: Relative bioavailability compared to marketed formulation.
Each value is represented in mean ± SD. .