Research Article

Mouse Prostate Epithelial Luminal Cells Lineage Originate in the Basal Layer Where the Primitive Stem/Early Progenitor Cells Reside: Implications for Identifying Prostate Cancer Stem Cells

Figure 1

Mouse prostate basal lineage development in mice, as determined by the cell fate tracking system. (a) Schematic representation of the generation of keratin 14-CreER/ROSA-LacZ mouse model. (b) PCR for CRE and LaZ expression in the keratin 14-CreER/Rosa-LacZ confirmed the successful generation of transgenic mice.
913179.fig.001a
(a)
913179.fig.001b
(b)