- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 915436, 10 pages
Bauhinia variegata Leaf Extracts Exhibit Considerable Antibacterial, Antioxidant, and Anticancer Activities
1Department of Biochemistry, University of Allahabad, Allahabad 211002, India
2Cancer Pharmacology Division, Indian Institute of Integrative Medicine, Jammu 180001, India
Received 30 April 2013; Accepted 1 August 2013
Academic Editor: Ivo Meinhold-Heerlein
Copyright © 2013 Amita Mishra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- I. N. Okeke, R. Laxminarayan, Z. A. Bhutta et al., “Antimicrobial resistance in developing countries. Part I: recent trends and current status,” The Lancet Infectious Diseases, vol. 5, no. 8, pp. 481–493, 2005.
- M. W. Iwu, A. R. Duncan, and C. O. Okunji, “New antimicrobials of plant origin,” in Perspectives on New Crops and New Uses, J. Janick, Ed., pp. 457–462, ASHS Press, Alexandria, Va, USA, 1999.
- A. Fabio, C. Cermelli, G. Fabio, P. Nicoletti, and P. Quaglio, “Screening of the antibacterial effects of a variety of essential oils on microorganisms responsible for respiratory infections,” Phytotherapy Research, vol. 21, no. 4, pp. 374–377, 2007.
- A. K. Bagchi, “Alternative medicine—old wine in a new bottle,” Journal of the Indian Medical Association, vol. 98, no. 6, pp. 332–333, 2000.
- A. K. Mishra, A. Mishra, A. Bhargava, and A. K. Pandey, “Antimicrobial activity of essential oils from the leaves of Cinnamomum spp,” National Academy Science Letters, vol. 31, no. 11-12, pp. 341–345, 2008.
- A. Maurya, P. Chauhan, A. Mishra, and A. K. Pandey, “Surface functionalization of TiO2 with plant extracts and their combined antimicrobial activities against E. faecalis and E. coli,” Journal of Research Updates in Polymer Sciences, vol. 1, pp. 43–51, 2012.
- D. S. Arora and P. Chandra, “Antioxidant activity of Aspergillus fumigates,” ISRN Pharmacology, vol. 2011, Article ID 619395, 11 pages, 2011.
- S. Kumar and A. K. Pandey, “Antioxidant, lipo-protective and antibacterial activities of phytoconstituents present in Solanum xanthocarpum root,” International Review of Biophysical Chemistry, vol. 3, no. 3, pp. 42–47, 2012.
- C. Rice-Evans, “Flavonoids and isoflavones: absorption, metabolism, and bioactivity,” Free Radical Biology and Medicine, vol. 36, no. 7, pp. 827–828, 2004.
- S. Chanda and R. Dave, “In Vitro models for antioxidant activity evaluation and some medicinal plants possessing antioxidant properties: an overview,” African Journal of Microbiology, vol. 3, no. 13, pp. 981–996, 2009.
- S. Cuzzocrea, D. P. Riley, A. P. Caputi, and D. Salvemini, “Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury,” Pharmacological Reviews, vol. 53, no. 1, pp. 135–159, 2001.
- P. N. Notani, “Global variation in cancer incidence and mortality,” Current Science, vol. 81, no. 5, pp. 465–474, 2001.
- S. H. Kaufmann and W. C. Earnshaw, “Induction of apoptosis by cancer chemotherapy,” Experimental Cell Research, vol. 256, no. 1, pp. 42–49, 2000.
- M. Verma, S. K. Singh, S. Bhushan et al., “In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial-dependent pathway in HL-60 cells,” Chemico-Biological Interactions, vol. 171, no. 1, pp. 45–56, 2008.
- P. Skehan, R. Storeng, D. Scudiero et al., “New colorimetric cytotoxicity assay for anticancer-drug screening,” Journal of the National Cancer Institute, vol. 82, no. 13, pp. 1107–1112, 1990.
- S. Jan, M. A. Khan, Sirajuddin, W. Murad, M. Hussain, and A. Ghani, “Herbal remedies used for gastrointestinal disorders in Kaghan valley, NWFP, Pakistan,” Pakistan Journal of Weed Science Research, vol. 14, pp. 169–200, 2008.
- Y. K. Rao, S.-H. Fang, and Y.-M. Tzeng, “Antiinflammatory activities of flavonoids and a triterpene caffeate isolated from Bauhinia variegata,” Phytotherapy Research, vol. 22, no. 7, pp. 957–962, 2008.
- A. K. Pandey, “Anti-staphylococcal activity of a pan-tropical aggressive and obnoxious weed Parihenium histerophorus: an in vitro study,” National Academy Science Letters, vol. 30, no. 11-12, pp. 383–386, 2007.
- A. K. Mishra, A. Mishra, H. K. Kehri, B. Sharma, and A. K. Pandey, “Inhibitory activity of Indian spice plant Cinnamomum zeylanicum extracts against Alternaria solani and Curvularia lunata, the pathogenic dematiaceous moulds,” Annals of Clinical Microbiology and Antimicrobials, vol. 8, article 9, 2009.
- E. A. Trease and B. Evans, Medicine and Plants, Pitman, London, UK, 3rd edition, 1983.
- E. A. Sofowora, Medicinal Plants and Traditional Medicine in Africa, John Wiley & Sons, London, UK, 2nd edition, 1993.
- C.-C. Chang, M.-H. Yang, H.-M. Wen, and J.-C. Chern, “Estimation of total flavonoid content in propolis by two complementary colometric methods,” Journal of Food and Drug Analysis, vol. 10, no. 3, pp. 178–182, 2002.
- S. Kumar, U. K. Sharma, A. K. Sharma, and A. K. Pandey, “Protective efficacy of Solanum xanthocarpum root extracts against free radical damage: phytochemical analysis and antioxidant effect,” Cellular and Molecular Biology, vol. 58, no. 1, pp. 171–178, 2012.
- A. W. Bauer, W. M. Kirby, J. C. Sherris, and M. Turck, “Antibiotic susceptibility testing by a standardized single disk method,” American Journal of Clinical Pathology, vol. 45, no. 4, pp. 493–496, 1966.
- C. Perez, M. Pauli, and P. Bazerque, “An antibiotic assay by the well agar method,” Acta Biologica Medicine Experiment, vol. 15, pp. 113–115, 1990.
- A. Volleková, D. Kostálová, and R. Sochorová, “Isoquinoline alkaloids from Mahonia aquifolium stem bark are active against Malassezia spp,” Folia Microbiologica, vol. 46, no. 2, pp. 107–111, 2001.
- M. Oyaizu, “Studies on products of browning reactions: antioxidative activities of products of browning reaction prepared from glucosamine,” Japanese Journal of Nutrition, vol. 44, pp. 307–315, 1986.
- A. K. Pandey, A. K. Mishra, A. Mishra, S. Kumar, and A. Chandra, “Therapeutic potential of C. zeylanicum extracts: an antifungal and antioxidant perspective,” International Journal of Biological and Medical Research, vol. 1, no. 4, pp. 228–233, 2010.
- T. C. P. Dinis, V. M. C. Madeira, and L. M. Almeida, “Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers,” Archives of Biochemistry and Biophysics, vol. 315, no. 1, pp. 161–169, 1994.
- G. K. Jayaprakasha, R. P. Singh, and K. K. Sakariah, “Antioxidant activity of grape seed (Vitis vinifera) extracts on peroxidation models in vitro,” Food Chemistry, vol. 73, no. 3, pp. 285–290, 2001.
- A. K. Pandey, A. K. Mishra, and A. Mishra, “Antifungal and antioxidative potential of oil and extracts derived from leaves of indian spice plant Cinnamomum tamala,” Cellular and Molecular Biology, vol. 58, no. 1, pp. 142–147, 2012.
- F. J. Hidalgo, M. M. León, and R. Zamora, “Effect of tocopherols in the antioxidative activity of oxidized lipid-amine reaction products,” Journal of Agricultural and Food Chemistry, vol. 55, no. 11, pp. 4436–4442, 2007.
- G. A. Pesewu, R. R. Cutler, and D. P. Humber, “Antibacterial activity of plants used in traditional medicines of Ghana with particular reference to MRSA,” Journal of Ethnopharmacology, vol. 116, no. 1, pp. 102–111, 2008.
- M. F. Mahomoodally, A. Gurib-Fakim, and A. H. Subratty, “Antimicrobial activities and phytochemical profiles of endemic medicinal plants of Mauritius,” Pharmaceutical Biology, vol. 43, no. 3, pp. 237–242, 2005.
- R. A. Dixon, P. M. Dey, and C. J. Lamb, “Phytoalexins: enzymology and molecular biology,” Advances in Enzymology, vol. 55, pp. 1–136, 1983.
- H. Tsuchiya, M. Sato, T. Miyazaki et al., “Comparative study on the antibacterial activity of phytochemical flavanones against methicillin-resistant Staphylococcus aureus,” Journal of Ethnopharmacology, vol. 50, no. 1, pp. 27–34, 1996.
- O. O. Aboaba and B. M. Efuwape, “Antibacterial properties of some Nigerian spices,” Biological Research Communication, vol. 13, pp. 183–188, 2001.
- J. Sikkema, J. A. M. De Bont, and B. Poolman, “Interactions of cyclic hydrocarbons with biological membranes,” Journal of Biological Chemistry, vol. 269, no. 11, pp. 8022–8028, 1994.
- A. K. Mishra, B. K. Singh, and A. K. Pandey, “In vitro antibacterial activity and phytochemicals of (Tejpat) leaf extracts and oil,” Reviews in Infection, vol. 1, pp. 134–139, 2010.
- S. Kumar, A. Mishra, and A. K. Pandey, “Antioxidant mediated protective effect of Parthenium hysterophorus against oxidative damage using in vitro models,” BMC Complementary and Alternative Medicine, vol. 13, article 120, 2013.
- S. Kumar and A. K. Pandey, “Phenolic content, reducing power and membrane protective activities of Solanum xanthocarpum root extracts,” Vegetos, vol. 26, pp. 301–307, 2013.
- M. Leopoldini, N. Russo, S. Chiodo, and M. Toscano, “Iron chelation by the powerful antioxidant flavonoid quercetin,” Journal of Agricultural and Food Chemistry, vol. 54, no. 17, pp. 6343–6351, 2006.
- R. C. Hider and A. D. Hall, “Clinically useful chelators of tripositive elements,” Progress in Medicinal Chemistry, vol. 28, pp. 41–173, 1991.
- R. Singh and S. Arora, “Attenuation of free radicals by acetone extract/fractions of Acacia nilotica (l) Willd. Ex del,” Journal of Chinese Clinical Medicine, vol. 2, pp. 196–204, 2007.
- M. H. Gordon, “The mechanism of the antioxidant action in vitro,” in Food Antioxidants, B. J. F. Hudson, Ed., pp. 1–18, Elsevier Applied Science, London, UK, 1990.
- M. R. Pérez-Gregorio, C. González-Barreiro, R. Rial-Otero, and J. Simal-Gándara, “Comparison of sanitizing technologies on the quality appearance and antioxidant levels in onion slices,” Food Control, vol. 22, no. 12, pp. 2052–2058, 2011.
- A. Mishra, S. Kumar, A. Bhargava, B. Sharma, and A. K. Pandey, “Studies on in vitro antioxidant and antistaphylococcal activities of some important medicinal plants,” Cellular and Molecular Biology, vol. 57, no. 1, pp. 16–25, 2011.
- G. M. Cragg and D. J. Newman, “Plants as a source of anti-cancer agents,” Journal of Ethnopharmacology, vol. 100, no. 1-2, pp. 72–79, 2005.
- B. Murray, R. Carter, C. Imrie, S. Evans, and C. O'Suilleabhain, “Diclofenac reduces the incidence of acute pancreatitis after endoscopic retrograde cholangiopancreatography,” Gastroenterology, vol. 124, no. 7, pp. 1786–1791, 2003.
- G. Weber, F. Shen, N. Prajda et al., “Increased signal transduction activity and down-regulation in human cancer cells,” Anticancer Research, vol. 16, no. 6A, pp. 3271–3282, 1996.
- T. Fotsis, M. S. Pepper, E. Aktas et al., “Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis,” Cancer Research, vol. 57, no. 14, pp. 2916–2921, 1997.
- B. Rajkapoor, N. Murugesh, and D. R. Krishna, “Cytotoxic activity of a flavanone from the stem of Bauhinia variegata linn,” Natural Product Research, vol. 23, no. 15, pp. 1384–1389, 2009.