Research Article
Comparative Study of Exome Copy Number Variation Estimation Tools Using Array Comparative Genomic Hybridization as Control
Table 1
Kullback-Leibler test on similarity with array CGH.
| ā | aCGH | cn.MOPS | exomeCopy | ExomeDepth | CoNIFER |
| Deletion CNVs proportion similarity | aCGH | 0 | 0.14 | 0.16 | 0.17 | 2.24 | cn.MOPS | 0.15 | 0 | 0.22 | 0.24 | 1.84 | exomeCopy | 0.16 | 0.23 | 0 | 0.2 | 1.88 | ExomeDepth | 0.22 | 0.27 | 0.23 | 0 | 2.56 | CoNIFER | 0.8 | 0.97 | 0.87 | 0.72 | 0 |
| Duplication CNVs proportion similarity | aCGH | 0 | 0.4 | 0.4 | 0.47 | 0.66 | cn.MOPS | 0.36 | 0 | 0.42 | 0.66 | 0.61 | exomeCopy | 0.42 | 0.59 | 0 | 0.18 | 0.26 | ExomeDepth | 0.55 | 1.06 | 0.25 | 0 | 0.55 | CoNIFER | 0.77 | 0.58 | 0.26 | 0.42 | 0 |
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