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BioMed Research International
Volume 2013 (2013), Article ID 918039, 7 pages
Antidiabetic Potential of the Heme Oxygenase-1 Inducer Curcumin Analogues
1Department of Anesthesiology and Pain Medicine, Wonkwang University School of Medicine, 460 Iksandae-ro, Iksan 570-749, Republic of Korea
2Department of Biological Science, University of Ulsan, 30 Daehack-ro, Ulsan 680-749, Republic of Korea
3Department of Microbiology and Immunology, Wonkwang University School of Medicine, 460 Iksandae-ro, Iksan 570-749, Republic of Korea
Received 8 June 2013; Accepted 29 August 2013
Academic Editor: Wilson João Cunico Filho
Copyright © 2013 Yong Son et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- J. Ye, “Mechanisms of insulin resistance in obesity,” Frontiers of Medicine, vol. 7, no. 1, pp. 14–24, 2013.
- A. D. Garg, A. Kaczmarek, O. Krysko, P. Vandenabeele, D. V. Krysko, and P. Agostinis, “ER stress-induced inflammation: does it aid or impede disease progression?” Trends in Molecular Medicine, vol. 18, no. 10, pp. 589–598, 2012.
- A. Leiherer, A. Mündlein, and H. Drexel, “Phytochemicals and their impact on adipose tissue inflammation and diabetes,” Vascular Pharmacology, vol. 58, no. 1-2, pp. 3–20, 2013.
- B. Meng, J. Li, and H. Cao, “Antioxidant and antiinflammatory activities of curcumin on diabetes mellitus and its complications,” Current Pharmaceutical Design, vol. 19, no. 11, pp. 2101–2113, 2013.
- P. Basnet and N. Skalko-Basnet, “Curcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatment,” Molecules, vol. 16, no. 6, pp. 4567–4598, 2011.
- J. M. Zingg, S. T. Hasan, and M. Meydani, “Molecular mechanisms of hypolipidemic effects of curcumin,” Biofactors, vol. 39, no. 1, pp. 101–121, 2013.
- U. Singh, A. Barik, B. G. Singh, and K. I. Priyadarsini, “Reactions of reactive oxygen species (ROS) with curcumin analogues: structure-activity relationship,” Free Radical Research, vol. 45, no. 3, pp. 317–325, 2011.
- A. Noorafshan and S. Ashkani-Esfahani, “A review of therapeutic effects of curcumin,” Current Pharmaceutical Design, vol. 19, no. 11, pp. 2032–2046, 2013.
- V. Calabrese, D. A. Butterfield, and A. M. G. Stella, “Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease,” The Italian Journal of Biochemistry, vol. 52, no. 4, pp. 177–181, 2003.
- H. O. Pae, Y. Son, N. H. Kim, H. J. Jeong, K. C. Chang, and H. Chung, “Role of heme oxygenase in preserving vascular bioactive NO,” Nitric Oxide, vol. 23, no. 4, pp. 251–257, 2010.
- H. O. Pae, E. C. Kim, and H. T. Chung, “Integrative survival response evoked by heme oxygenase-1 and heme metabolites,” Journal of Clinical Biochemistry and Nutrition, vol. 42, no. 3, pp. 197–203, 2008.
- N. G. Abraham, “Heme oxygenase: a target gene for anti-diabetic and obesity,” Current Pharmaceutical Design, vol. 14, no. 5, pp. 412–421, 2008.
- G. D. Stoner, L. Wang, and B. C. Casto, “Laboratory and clinical studies of cancer chemoprevention by antioxidants in berries,” Carcinogenesis, vol. 29, no. 9, pp. 1665–1674, 2008.
- M. Reth, “Hydrogen peroxide as second messenger in lymphocyte activation,” Nature Immunology, vol. 3, no. 12, pp. 1129–1134, 2002.
- M. Valko, D. Leibfritz, J. Moncol, M. T. D. Cronin, M. Mazur, and J. Telser, “Free radicals and antioxidants in normal physiological functions and human disease,” International Journal of Biochemistry and Cell Biology, vol. 39, no. 1, pp. 44–84, 2007.
- W. Ying, “NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences,” Antioxidants and Redox Signaling, vol. 10, no. 2, pp. 179–206, 2008.
- A. Bloch-Damti, R. Potashnik, P. Gual et al., “Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress,” Diabetologia, vol. 49, no. 10, pp. 2463–2473, 2006.
- T. Finkel, “Signal transduction by reactive oxygen species,” Journal of Cell Biology, vol. 194, no. 1, pp. 7–15, 2011.
- D. Tang, R. Kang, C. B. Coyne, H. J. Zeh, and M. T. Lotze, “PAMPs and DAMPs: signal 0s that spur autophagy and immunity,” Immunological Reviews, vol. 249, no. 1, pp. 158–175, 2012.
- M. B. Fessler, L. L. Rudel, and J. M. Brown, “Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome,” Current Opinion in Lipidology, vol. 20, no. 5, pp. 379–385, 2009.
- G. S. Hotamisligil, P. Arner, J. F. Caro, R. L. Atkinson, and B. M. Spiegelman, “Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance,” Journal of Clinical Investigation, vol. 95, no. 5, pp. 2409–2415, 1995.
- M. Wang, “The role of glucocorticoid action in the pathophysiology of the Metabolic Syndrome,” Nutrition and Metabolism, vol. 2, no. 1, p. 3, 2005.
- H. B. Stoner, R. A. Little, and K. N. Frayn, “The effect of sepsis on the oxidation of carbohydrate and fat,” British Journal of Surgery, vol. 70, no. 1, pp. 32–35, 1983.
- C. J. Tack, R. Stienstra, L. A. Joosten, and M. G. Netea, “Inflammation links excess fat to insulin resistance: the role of the interleukin-1 family,” Immunological Reviews, vol. 249, no. 1, pp. 239–252, 2012.
- H. P. Kim, H. Pae, S. H. Back et al., “Heme oxygenase-1 comes back to endoplasmic reticulum,” Biochemical and Biophysical Research Communications, vol. 404, no. 1, pp. 1–5, 2011.
- K. M. Kim, H. Pae, M. Zheng, R. Park, Y. Kim, and H. Chung, “Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress,” Circulation Research, vol. 101, no. 9, pp. 919–927, 2007.
- K. Poss and S. Tonegawa, “Heme oxygenase 1 is required for mammalian iron reutilization,” Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 20, pp. 10919–10924, 1997.
- L. D. Orozco, M. H. Kapturczak, B. Barajas et al., “Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis,” Circulation Research, vol. 100, no. 12, pp. 1703–1711, 2007.
- A. Yachie, Y. Niida, T. Wada et al., “Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency,” Journal of Clinical Investigation, vol. 103, no. 1, pp. 129–135, 1999.
- J. Clark, R. Foresti, C. J. Green, and R. Motterlini, “Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress,” Biochemical Journal, vol. 348, no. 3, pp. 615–619, 2000.
- G. Balla, H. S. Jacob, J. Balla et al., “Ferritin: a cytoprotective antioxidant strategem of endothelium,” Journal of Biological Chemistry, vol. 267, no. 25, pp. 18148–18153, 1992.
- X. M. Liu, K. J. Peyton, D. Ensenat et al., “Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle: role in cell survival,” Journal of Biological Chemistry, vol. 280, no. 2, pp. 872–877, 2005.
- E. Balogun, M. Hoque, P. Gong et al., “Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element,” Biochemical Journal, vol. 371, no. 3, pp. 887–895, 2003.
- H. O. Pae, G. S. Jeong, S. O. Jeong et al., “Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells,” Experimental and Molecular Medicine, vol. 39, no. 3, pp. 267–277, 2007.
- S. O. Jeong, G. S. Oh, H. Y. Ha et al., “Dimethoxycurcumin, a synthetic curcumin analogue, induces heme oxygenase-1 expression through Nrf2 activation in RAW264.7 macrophages,” Journal of Clinical Biochemistry and Nutrition, vol. 44, no. 1, pp. 79–84, 2009.
- G. S. Jeong, G. S. Oh, H. O. Pae et al., “Comparative effects of curcuminoids on endothelial heme oxygenase-1 expression: ortho-methoxy groups are essential to enhance heme oxygenase activity and protection,” Experimental and Molecular Medicine, vol. 38, no. 4, pp. 393–400, 2006.
- L. Zhongfa, M. Chiu, J. Wang et al., “Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice,” Cancer Chemotherapy and Pharmacology, vol. 69, no. 3, pp. 679–689, 2012.
- C. Tamvakopoulos, K. Dimas, Z. D. Sofianos et al., “Metabolism and anticancer activity of the curcumin analogue, dimethoxycurcumin,” Clinical Cancer Research, vol. 13, no. 4, pp. 1269–1277, 2007.
- M. T. Aziz, I. N. El Ibrashy, D. P. Mikhailidis, et al., “Signaling mechanisms of a water soluble curcumin derivative in experimental type 1 diabetes with cardiomyopathy,” Diabetology & Metabolic Syndrome, vol. 5, no. 1, p. 13, 2013.