Catecholaminergic Gene Variants: Contribution in ADHD and Associated Comorbid Attributes in the Eastern Indian Probands

Table 2

Genotypic frequencies in controls compared with that of ADHD probands and their parents.

Site	Genotypes	Control; (𝑁=180)	P value for HWE	Case; (𝑁=170)	P value for HWE	𝜒^2; (P)	Parent; (𝑁=310)	P value for HWE	𝜒^2; (P)
rs3837091	(Del/Del)	0.19	0.06	0.13	0.16	1.64 (0.44)	0.17	0.08	0.16 (0.93)
	(Del/AGAG)	0.36		0.35			0.36
	(AGAG/AGAG)	0.45		0.52			0.47
rs3735273	GG	0.57	0.41	0.49	0.84	1.42 (0.49)	0.51	0.14	1.63 (0.44)
	GA	0.35		0.43			0.38
	AA	0.08		0.08			0.11
rs1800496	CC	1.00	—	1.00	—	—	1.00	—	—
	CT	0.00		0.00			0.00
	TT	0.00		0.00			0.00
rs1801028	CC	1.00	—	1.00	—	—	1.00	—	—
	CG	0.00		0.00			0.00
	GG	0.00		0.00			0.00
rs1799732	CC	0.78	0.17	0.83	0.14	0.826; (0.662)	0.80	0.13	0.252; (0.89)
	C/Del	0.19		0.15			0.18
	Del/Del	0.03		0.02			0.02
rs4646984	1R1R	0.07	1.00	0.09	0.85	0.80; (0.67)	0.10	1.00	1.21; (0.55)
	1R2R	0.40		0.44			0.44
	2R2R	0.53		0.47			0.46
rs4646983	1R1R	0.00	0.60	0.04	0.32	4.80; (0.09)	0.03	0.20	3.70; (0.16)
	1R2R	0.19		0.23			0.23
	2R2R	0.81		0.73			0.74
rs165599	GG	0.06	0.03	0.12	0.06	1.19; (0.55)	0.14	0.78	3.59; (0.17)
	GA	0.56		0.57			0.50
	AA	0.38		0.31			0.36
rs740603	GG	0.26	0.18	0.30	0.86	1.69; (0.43)	0.24	0.37	1.84; (0.40)
	GA	0.44		0.48			0.53
	AA	0.30		0.22			0.23