Synthesis of a Novel Thiazolidinedione and Evaluation of Its Modulatory Effect on IFN-γ, IL-6, IL-17A, and IL-22 Production in PBMCs from Rheumatoid Arthritis Patients
Figure 2
Evaluation of proinflammatory cytokines release inhibition by TM17 compound in splenocytes culture. (a) TM17 inhibits the release of IL17A in a dose-dependent manner. (b) IL6 was significantly inhibited by TM17 in all tested doses. (c) TM17 decreases IFNγ release mainly in 10 μM. .