Research Article

Synthesis of a Novel Thiazolidinedione and Evaluation of Its Modulatory Effect on IFN-γ, IL-6, IL-17A, and IL-22 Production in PBMCs from Rheumatoid Arthritis Patients

Figure 5

PPARγ expression in PBMCs from healthy individuals. (a) PPARy mRNA fold increase in cells treated with rosiglitazone and TM17 compound at 100 μM concentration. (b) Iono and PMA enhance PPARγ expression, and TM17 and rosiglitazone reduce significantly PPARγ mRNA in this condition. .
926060.fig.005a
(a)
926060.fig.005b
(b)