Table 3: Antimycobacterial activity of compounds 5a–g against M. tuberculosis H37Rv and INH-resistant Mycobacterium tuberculosis.

926309.table.003
CompoundMICa
(µM)
MICb
(µM)
6.12 cytotoxicity
(µg/mL)

5a6.21964.78>62.5
5b0.19524.12>62.5
5c4.32026.12>62.5
5d0.13516.25>62.5
5e6.1952.10>62.5
5f6.21941.72>62.5
5g0.1126.12>62.5
Isoniazid0.7311.37>62.5

Mycobacterium tuberculosis H37Rv and bINH-resistant Mycobacterium tuberculosis.