TET2 Mutations in Ph-Negative Myeloproliferative Neoplasms: Identification of Three Novel Mutations and Relationship with Clinical and Laboratory Findings

Table 2

TET2 mutations in MPN patients.

	Sequence location	Effect	cDNA	Patient ID (diagnosis)
p.P177fs	Exon 3	Frameshift	c.530delC	P39 (MPN-U)
p.P411del	Exon 3	Deletion	c.1232_1234delCCT	P98 (TE)
p.C1298del	Exon 7	Deletion	c.3890_3892delGAT	P42 (MPN-U)
p.Q652fs*	Exon 3	Frameshift	c.1954delC	P65 (MPN-U)
p.R1572W*	Exon 11	Missense	c.4714C>T	P23 (PV)
p.V1718L*	Exon 11	Missense	c.5152G>T	P21, P25 (TE, PV)

 *Novel mutations.