Research Article

DPYD, TYMS, TYMP, TK1, and TK2 Genetic Expressions as Response Markers in Locally Advanced Rectal Cancer Patients Treated with Fluoropyrimidine-Based Chemoradiotherapy

Figure 3

Receiver-operating characteristic (ROC) curve analysis of weighted enzymatic chip array in 60 rectal cancer tissues. In ROC curve analysis of 5 target genes, at a cutoff value of 3 positive genes, a sensitivity of 89.7% and specificity of 81% were obtained (area under ROC curve (AUC): 0.915; and the corresponding 95% confidence intervals (CI): 0.840–0.991) were considered positive results.
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