DPYD, TYMS, TYMP, TK1, and TK2 Genetic Expressions as Response Markers in Locally Advanced Rectal Cancer Patients Treated with Fluoropyrimidine-Based Chemoradiotherapy

Table 2

The area under the ROC curve (AUC) and the corresponding 95% confidence intervals (CI) of 9 genes.

Gene	AUC	95% CI
DPYD	0.815	0.711–0.919
TYMS	0.836	0.734–0.939
TYMP	0.81	0.701–0.918
ORPT	0.683	0.54–0.827
GLUT1	0.743	0.605–0.881
HIF-1 𝛼	0.514	0.355–0.673
HIF-2 𝛼	0.601	0.449–0.754
TK1	0.798	0.682–0.914
TK2	0.852	0.759–0.946