931564.fig.001a
(a)
931564.fig.001b
(b)
931564.fig.001c
(c)
931564.fig.001d
(d)
931564.fig.001e
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931564.fig.001f
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931564.fig.001g
(g)
931564.fig.001h
(h)
Figure 1: Speckles in mouse embryo nuclei at different stages of embryogenesis after immunolabeling with anti-SC35 antibody. Discrete speckles are revealed on the background of diffuse fluorescence of the nucleoplasm at all studied stages. However, the speckles in mouse embryo nuclei, especially at earlier stages, have much smaller size as compared with somatic speckles ((a)–(f)). Only in some late 2-cell embryo (g) and in 4-cell embryos (h) IGC size is similar to the size of IGCs in somatic cells. Unstained roundish areas in the nuclei correspond to the nucleolar precursor bodies (NPBs). Bar is 10 μm.