Kidney Dosimetry in ¹⁷⁷Lu and ⁹⁰Y Peptide Receptor Radionuclide Therapy: Influence of Image Timing, Time-Activity Integration Method, and Risk Factors

Figure 6

𝐷 and BED in case of ¹⁷⁷Lu therapy (upper panels) and ⁹⁰Y therapy (lower panels). The histograms report mean and 1 SD. ¹⁷⁷Lu and ⁹⁰Y-therapy administer a similar total dose for the specific schemes considered (29.8 GBq in 4 cycles versus 7.4 GBq in 2 cycles, resp.). Conversely, BED is noticeably greater for ⁹⁰Y because of the lower fractionation. Mean ± SD values are similar, but relevant differences among patients can be found (see also Figure 4).

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