Research Article
Analysis of COCH and TNFA Variants in East Indian Primary Open-Angle Glaucoma Patients
Table 4
Genotype frequency distribution of two SNPs of TNFA promoter in patients and controls.
| SNP | Genotype | Genotypic frequency in patients | Genotypic frequency in controls | P value | OR (95% CI) |
| rs361525 (−238 G/A) | GG | 0.81 | 0.833 | 0.567 | 0.855 (0.533–1.370) | GA | 0.175 | 0.16 | 0.712 | 1.120 (0.619–1.818) | AA | 0.015 | 0.007 | 0.686 | 1.932 (0.302–15.301) |
| rs1800629 (−308 G/A) | GG | 0.918 | 0.911 | 0.876 | 1.099 (0.572–2.112) | GA | 0.078 | 0.089 | 0.753 | 0.865 (0.447–1.673) | AA | 0.004 | 0 | — | — |
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