Anti-Inflammatory Effects of Arsenic Trioxide Eluting Stents in a Porcine Coronary Model

<table>Immunohistochemical staining (a) and western blotting analysis (b) of arteries treated with BMSs, PCSs, and AESs for 4 weeks after stent implantation. The stent-based As<sub>2</sub>O<sub>3</sub> delivery significantly reduced the expression of proteins MCP-1, IL-6, and CD3 (<svg height="11.375" id="M31" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). In western blotting analysis, the expression of MCP-1 and IL-6 in the arteries treated with AESs was significantly lower than BMSs and PCSs (<svg height="11.375" id="M32" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>).</table>

BioMed Research International

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Figure 4

Figure 4: Anti-Inflammatory Effects of Arsenic Trioxide Eluting Stents in a Porcine Coronary Model 