Research Article
Evaluation of Adverse Effects of Mutein Forms of Recombinant Human Interferon Alpha-2b in Female Swiss Webster Mice
Table 1
Mortalities and LD50 values of female Swiss Webster mice after a single subcutaneous administration of wild type rIFN-α2b or mutein rIFN-α2bC2DC99D.
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D1 = 97.5 g/kg BW, D2 = 975 g/kg BW, and D3 = 9.75 mg/g BW. |