Table 3: Organ indices of female mice after subcutaneous administration of wild type rIFN-α2b or rIFN-α2bC2DC99D once every 3 days during a 45-day period.

OrganControlGroups
Wild type rIFN-α2b (D4)rIFN-α2bC2DC99D (D4)Wild type rIFN-α2b (D5)rIFN-α2bC2DC99D (D5)

Heart0.43 ± 0.030.41 ± 0.0130.41 ± 0.040.43 ± 0.030.41 ± 0.03
Liver5.81 ± 0.395.95 ± 0.336.14 ± 1.065.97 ± 0.555.39 ± 0.26
Kidney1.37 ± 0.161.39 ± 0.161.48 ± 0.071.34 ± 0.051.30 ± 0.12
Limp0.66 ± 0.150.59 ± 0.140.72 ± 0.180.58 ± 0.140.48 ± 0.09
Ovary-uterus0.69 ± 0.160.64 ± 0.120.78 ± 0.140.72 ± 0.190.69 ± 0.19
Lung0.59 ± 0.070.58 ± 0.020.60 ± 0.090.61 ± 0.050.59 ± 0.07

D4 = 1.95  g/kg BW, D5 = 19.5  g/kg BW.