Table 8: (a) The 50% growth inhibition (GI50) data of different Conyza extracts in 6 cell lines. (b) The total growth inhibition (TGI) data of different Conyza extracts in 6 cell lines. (c) The 50% lethality (LC50) data of different Conyza extracts in 6 cell lines.
(a)

ExtractPotency of extracts (μg) in cell lines (mean ± SEM); n = 3
HT29A549PC3MCF7Hepa1C1C7H4IIE1

I0.93 ± 0.10 4.07 ± 0.311.00 ± 0.0543.77 ± 3.020.70 ± 0.040.93 ± 0.04
II0.47 ± 0.05 0.17 ± 0.010.60 ± 0.0228.13 ± 1.870.10 ± 0.010.07 ± 0.01
III0.47 ± 0.02 0.27 ± 0.010.67 ± 0.0310.00 ± 0.790.07 ± 0.020.10 ± 0.01
IV0.77 ± 0.04 0.43 ± 0.030.87 ± 0.0510.00 ± 0.880.07 ± 0.010.07 ± 0.02
V0.77 ± 0.0748.43 ± 4.006.10 ± 0.53 8.43 ± 0.511.00 ± 0.070.77 ± 0.06

(b)

ExtractPotency of extracts (μg) in cell lines (mean ± SEM); n = 3
HT29A549PC3MCF7Hepa1C1C7H4IIE1

I6.3 ± 0.51 50.0 ± 6.21 7.7 ± 0.44375.0 ± 29.12 a 6.0 ± 0.417.0 ± 0.91
II1.7 ± 0.01 1.9 ± 0.07 7.0 ± 0.52281.3 ± 31.04 a 0.7 ± 0.340.3 ± 0.02
III2.0 ± 0.09 1.6 ± 0.02 6.7 ± 0.47 71.7 ± 5.55 0.3 ± 0.220.7 ± 0.01
IV5.7 ± 0.49 3.3 ± 0.02 7.0 ± 0.34 56.3 ± 4.67 0.3 ± 0.240.7 ± 0.03
V5.3 ± 0.61437.0 ± 41.11a478.7 ± 39.29 a 46.7 ± 6.0034.3 ± 4.018.0 ± 1.01

(c)

ExtractPotency of extracts (μg) in cell lines (mean ± SEM), n = 3
HT29A549PC3MCF7Hepa1C1C7H4IIE1

I37.3 ± 4.5845.0 ± 98.4a64.0 ± 5.9>1000a 48.7 ± 5.356.3 ± 6.1
II10.0 ± 2.1 21.7 ± 3.471.7 ± 6.4>1000a 3.0 ± 2.4 2.0 ± 0.5
III19.0 ± 1.8 10.0 ± 1.537.7 ± 2.8375.0 ± 40.1a 2.3 ± 1.6 2.0 ± 0.4
IV31.3 ± 2.5 91.0 ± 8.718.7 ± 3.3193.7 ± 21.9 1.7 ± 0.7 4.0 ± 0.3
V25.7 ± 2.7>1000a>1000a100.0 ± 11.1130.0 ± 9.9a65.7 ± 8.0

Extrapolated from dose-response curve. HT29 (human colon), A549 (human lung), PC3 (human prostate), MCF7 (human breast), Hepa1C1C7 (murine liver), and H4IIE1 (rat liver). GI50 is the concentration of an extract (μg) that causes 50% growth inhibition. TGI is the concentration of an extract (μg) that yields no net growth over the course of the assay. LC50 is the concentration of an extract (μg) that kills 50% of the cells that were present at the time of the addition of the extract.