Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection

Table 1

Demographic and biochemical characteristics in the study population.

	All subjects; (𝑛=50)	Without AKI; (𝑛=28)	With AKI; (𝑛=22)
Age (months)*	6.00 (4.00–7.00)	3.3 (2.37–4.40)	11.7 (7.07–18.12)
Gender, male (%)	56	61.5	38.5
BMI (kg/m^2)	11.67±4.29	10.36±2.02	12.88±5.69^a
Fever (°C)	39.22±0.658	39.17±0.58	39.22±0.77
Duration of fever (days)	3.1±1.45	2.74±1.29	3.75±1.52^a
Duration in hospital (days)*	5.46 (5.00–6.00)	5.41 (4.24–6.90)	5.89 (5.21–7.61)
GFR (mL/min/m^2)	49.20±13.34	51.13±10.07	40.42±12.49
sCr (µmol/L)	57.85±13.99	50.70±7.56	65.40±15.60
Urea (mmol/L)*	2.87 (2.50–3.31)	2.47 (2.06–2.98)	3.40 (2.61–4.42)^a
Leukocyte number (×10e9/L)	17.55±5.92	16.38±5.16	19.12±6.5^a
Urine culture (%)
Escherichia coli	88	90.9	85.0
Klebsiella	4.8	4.5	5
Proteus	4.8	0	10
Other	2.4	4.5	0
Therapy (%)
Longaceph (ceftriaxone)	38.6	39.1	38.1
Amikacin	36.4	30.4	42.9
Combination	25.0	30.5	19.0

Data are mean ± SD, percentages, or *geometrical mean (95% CI for the mean) for variables with skewed distribution. ^asignificantly different from group without AKI by Student t-test.