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BioMed Research International
Volume 2013 (2013), Article ID 953520, 6 pages
Effects of Nigella sativa and Lepidium sativum on Cyclosporine Pharmacokinetics
1Department of Pharmaceutics, College of Pharmacy, King Saud University Riyadh, P.O. Box 2457, Riyadh 11451, Saudi Arabia
2Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University Riyadh, Riyadh 11451, Saudi Arabia
3Department of Clinical Pharmacy, College of Pharmacy, King Saud University Riyadh, Riyadh 11451, Saudi Arabia
4Department of Pharmacology, College of Pharmacy, King Saud University Riyadh, Riyadh 11451, Saudi Arabia
Received 4 April 2013; Revised 3 June 2013; Accepted 18 June 2013
Academic Editor: Shigeru Satoh
Copyright © 2013 F. I. Al-Jenoobi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- V. A. Bhattaram, U. Graefe, C. Kohlert, M. Veit, and H. Derendorf, “Pharmacokinetics and bioavailability of herbal medicinal products,” Phytomedicine, vol. 9, supplement 3, pp. 1–33, 2002.
- P. K. Mukherjee and A. Wahile, “Integrated approaches towards drug development from Ayurveda and other Indian system of medicines,” Journal of Ethnopharmacology, vol. 103, no. 1, pp. 25–35, 2006.
- S. Shi and U. Klotz, “Drug interactions with herbal medicines,” Clinical Pharmacokinetics, vol. 51, no. 2, pp. 77–104, 2012.
- C. Tarirai, A. M. Viljoen, and J. H. Hamman, “Herb-drug pharmacokinetic interactions reviewed,” Expert Opinion on Drug Metabolism and Toxicology, vol. 6, no. 12, pp. 1515–1538, 2010.
- Z.-Z. Fang, Y.-Y. Zhang, G.-B. Ge et al., “Identification of cytochrome P450 (CYP) isoforms involved in the metabolism of corynoline, and assessment of its herb-drug interactions,” Phytotherapy Research, vol. 25, no. 2, pp. 256–263, 2011.
- Y.-L. Han, H.-L. Yu, D. Li et al., “In vitro inhibition of huanglian [Rhizoma coptidis (L.)] and its six active alkaloids on six cytochrome P450 isoforms in human liver microsomes,” Phytotherapy Research, vol. 25, no. 11, pp. 1660–1665, 2011.
- S. H. Y. Ho, M. Singh, A. C. Holloway, and D. J. Crankshaw, “The effects of commercial preparations of herbal supplements commonly used by women on the biotransformation of fluorogenic substrates by human cytochromes P450,” Phytotherapy Research, vol. 25, no. 7, pp. 983–989, 2011.
- J. Doehmer and J. Eisenbraun, “Assessment of extracts from mistletoe (Viscum album) for herb-drug interaction by inhibition and induction of cytochrome P450 activities,” Phytotherapy Research, vol. 26, no. 1, pp. 11–17, 2012.
- J. Boullata, “Natural health product interactions with medication,” Nutrition in Clinical Practice, vol. 20, no. 1, pp. 33–51, 2005.
- A. A. Izzo and E. Ernst, “Interactions between herbal medicines and prescribed drugs: a systematic review,” Drugs, vol. 61, no. 15, pp. 2163–2175, 2001.
- D. Faulds, K. L. Goa, and P. Benfield, “Cyclosporin: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders,” Drugs, vol. 45, no. 6, pp. 953–1040, 1993.
- S. Noble and A. Markham, “Cyclosporin: a review of the pharmacokinetic properties, clinical efficacy and tolerability of a microemulsion-based formulation (Neoral),” Drugs, vol. 50, no. 5, pp. 924–941, 1995.
- T. Kajita, Y. Higashi, M. Imamura et al., “Effect of imatinib mesilate on the disposition kinetics of ciclosporin in rats,” Journal of Pharmacy and Pharmacology, vol. 58, no. 7, pp. 997–1000, 2006.
- X. P. Xue, X. L. Qin, C. Xu et al., “Effect of Wuzhi tablet (Schisandra sphenanthera extract) on the pharmacokinetics of cyclosporine A in rats,” Phytotherapy Research, 2012.
- S.-L. Hsiu, Y.-C. Hou, Y.-H. Wang, C.-W. Tsao, S.-F. Su, and P.-D. L. Chao, “Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats,” Life Sciences, vol. 72, no. 3, pp. 227–235, 2002.
- T. Yokooji, M. Kida, M. Mori et al., “Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats,” Die Pharmazie, vol. 65, no. 5, pp. 367–374, 2010.
- H.-M. Chiang, P.-D. L. Chao, S.-L. Hsiu, K.-C. Wen, S.-Y. Tsai, and Y.-C. Hou, “Ginger significantly decreased the oral bioavailability of cyclosporine in rats,” American Journal of Chinese Medicine, vol. 34, no. 5, pp. 845–855, 2006.
- C. Y. Yang, P. D. L. Chao, Y. C. Hou, S. Y. Tsai, K. C. Wen, and S. L. Hsiu, “Marked decrease of cyclosporin bioavailability caused by coadministration of ginkgo and onion in rats,” Food and Chemical Toxicology, vol. 44, no. 9, pp. 1572–1578, 2006.
- H. Gali-Muhtasib, A. Roessner, and R. Schneider-Stock, “Thymoquinone: a promising anti-cancer drug from natural sources,” International Journal of Biochemistry and Cell Biology, vol. 38, no. 8, pp. 1249–1253, 2006.
- M. Khader, N. Bresgen, and P. M. Eckl, “In vitro toxicological properties of thymoquinone,” Food and Chemical Toxicology, vol. 47, no. 1, pp. 129–133, 2009.
- T. A. Gheita and S. A. Kenawy, “Effectiveness of Nigella sativa oil in the management of rheumatoid arthritis patients: a placebo controlled study,” Phytotherapy Research, vol. 26, no. 8, pp. 1246–1248, 2012.
- A. H. Gilani, N. U. Rehman, M. H. Mehmood, and K. M. Alkharfy, “Species differences in the antidiarrheal and antispasmodic activities of Lepidium sativum and insight into underlying mechanisms,” Phytotherapy Research, 2012.
- N.-U. Rehman, A.-U. Khan, K. M. Alkharfy, and A.-H. Gilani, “Pharmacological basis for the medicinal use of Lepidium sativum in airways disorders,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 596524, 8 pages, 2012.
- S. B. Vohora and M. S. Y. Khan, “Pharmacological studies on Lepidium sativum, Linn,” Indian Journal of Physiology and Pharmacology, vol. 21, no. 2, pp. 118–120, 1977.
- P. A. G. M. de Smet, “The role of plant-derived drugs and herbal medicines in healthcare,” Drugs, vol. 54, no. 6, pp. 801–840, 1997.
- J. Grenier, C. Fradette, G. Morelli, G. J. Merritt, M. Vranderick, and M. P. Ducharme, “Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans,” Clinical Pharmacology and Therapeutics, vol. 79, no. 3, pp. 255–262, 2006.
- M.-Y. Lai, S.-L. Hsiu, Y.-C. Hou, S.-Y. Tsai, and P.-D. L. Chao, “Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis,” Planta Medica, vol. 70, no. 2, pp. 132–137, 2004.
- S. Hedayati, A. Bernareggi, and M. Rowland, “Absorption kinetics of cyclosporin in the rat,” Journal of Pharmacy and Pharmacology, vol. 44, no. 2, pp. 122–124, 1992.
- K. S. Lown, J. C. Kolars, K. E. Thummel et al., “Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel,” Drug Metabolism and Disposition, vol. 22, pp. 947–955, 1994.
- A. Fahr, “Cyclosporin clinical pharmacokinetics,” Clinical Pharmacokinetics, vol. 24, no. 6, pp. 472–495, 1993.
- R. D. Whalen, P. N. V. Tata, G. J. Burckart, and R. Venkataramanan, “Species differences in the hepatic and intestinal metabolism of cyclosporine,” Xenobiotica, vol. 29, no. 1, pp. 3–9, 1999.
- R. Venkataramanan, C. P. Wang, K. Habucky et al., “Species-specific cyclosporine metabolism,” Transplantation Proceedings, vol. 20, no. 2, pp. 680–683, 1988.