The Associated Ion between the VDR Gene Polymorphisms and Susceptibility to Hepatocellular Carcinoma and the Clinicopathological Features in Subjects Infected with HBV

Table 4

The genotype frequencies of VDR gene in HCC patients with chronic HBV infection and HCC patient without HBV infection.

	HCC with HBV		HCC without HBV		Adjusted OR	95% CI		Adjusted 𝑃 value
BsmI
GG	112	25.69%	37	28.24%	1.000
GA	217	49.77%	65	49.62%	1.103	0.694	1.753	0.679
AA	107	24.54%	29	22.14%	1.219	0.701	2.120	0.483
G	441	50.57%	139	53.05%	1.000
A	431	49.43%	123	46.95%	1.104	0.838	1.456	0.481
FokI
CC	107	24.54%	31	23.66%	1.000
CT	198	45.41%	62	47.33%	0.925	0.566	1.512	0.756
TT	131	30.05%	38	29.01%	0.999	0.583	1.712	0.745
C	412	47.25%	124	47.33%	1.000
T	460	52.75%	138	52.67%	1.003	0.761	1.323	0.982
ApaI
GG	108	24.77%	22	16.79%	1.000
GT	216	49.54%	75	57.25%	0.587	0.346	0.995	0.052
TT	112	25.69%	34	25.95%	0.671	0.369	1.220	0.571
G	432	49.54%	119	45.42%	1.000
T	440	50.46%	143	54.58%	0.848	0.642	1.118	0.242
TaqI
TT	115	26.38%	32	24.43%	1.000
TC	212	48.62%	69	52.67%	0.855	0.531	1.377	0.519
CC	109	25.00%	30	22.90%	1.011	0.576	1.775	0.970
T	442	50.69%	133	50.76%	1.000
C	430	49.31%	129	49.24%	1.003	0.761	1.322	0.983