Killing Effect of Ad5/F35-APE1 siRNA Recombinant Adenovirus in Combination with Hematoporphrphyrin Derivative-Mediated Photodynamic Therapy on Human Nonsmall Cell Lung Cancer
Figure 5
Expression of APE1 in A549 cells was knocked down by Ad5/F35-APE1siRNA in a time- and dose-dependent manner via Western blot assay. (a) Time-effect relationship of APE1 protein expression knocked down by Ad5/F35-APE1 siRNA. (b) Dose-effect relationship of the APE1 protein expression knocked down by Ad5/F35-APE1 siRNA. (c) Efficient knock down effect by Ad5/F35-APE1 siRNA on PDT-induced APE1 upregulation.
