About this Journal Submit a Manuscript Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 958465, 8 pages
http://dx.doi.org/10.1155/2013/958465
Research Article

Formulation and Evaluation of Chitosan-Chondroitin Sulphate Based Nasal Inserts for Zolmitriptan

Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab 147002, India

Received 25 April 2013; Accepted 26 August 2013

Academic Editor: Shirui Mao

Copyright © 2013 Kirandeep Kaur and Gurpreet Kaur. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Gupta, S. Mehrotra, C. M. Villalón, M. Perusquía, P. R. Saxena, and A. MaassenVanDenBrink, “Potential role of female sex hormones in the pathophysiology of migraine,” Pharmacology and Therapeutics, vol. 113, no. 2, pp. 321–340, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. H. U. Sheikh and P. G. Mathew, “Acute and preventive treatment of migraine attacks,” Techniques in Regional Anesthesia and Pain Management, vol. 16, no. 1, pp. 19–24, 2012.
  3. S. K. Aurora, S. H. Kori, P. Barrodale, S. A. McDonald, and D. Haseley, “Gastric stasis in migraine: more than just a paroxysmal abnormality during a migraine attack,” Headache, vol. 46, no. 1, pp. 57–63, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. Y. Chugh, P. Kapoor, and A. K. Kapoor, “Intranasal drug delivery: a novel approach,” Indian Journal of Otolaryngology and Head and Neck Surgery, vol. 61, no. 2, pp. 90–94, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Touitou and L. Illum, “Nasal drug delivery,” Drug Delivery and Translational Research, vol. 3, no. 1, pp. 1–3, 2013.
  6. U. Bertram and R. Bodmeier, “Parameters affecting the drug release from in situ gelling nasal inserts,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 63, no. 3, pp. 310–319, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. R. C. Glen, G. R. Martin, A. P. Hill et al., “Computer-aided design and synthesis of 5-substituted tryptamines and their pharmacology at the 5-HT1D receptor: discovery of compounds with potential anti-migraine properties,” Journal of Medicinal Chemistry, vol. 38, no. 18, pp. 3566–3580, 1995. View at Scopus
  8. A. M. Ropoport, M. E. Bigal, S. J. Tepper, and F. D. Sheftell, “Zolmitriptan (Zomig),” Expert Review of Neurotherapeutics, vol. 4, no. 1, pp. 33–41, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. S. S. Bhattacharya, S. Shukla, S. Banerjee, et al., “Tailored IPN hydrogel bead of sodium carboxymethyl cellulose and sodium carboxymethyl xanthan gum for controlled delivery of diclofenac sodium,” Polymer-Plastics Technology Engineering, vol. 52, no. 8, pp. 795–805, 2013.
  10. M. Thanou, J. C. Verhoef, and H. E. Junginger, “Oral drug absorption enhancement by chitosan and its derivatives,” Advanced Drug Delivery Reviews, vol. 52, no. 2, pp. 117–126, 2001. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Bernkop-Schnürch and S. Dünnhaupt, “Chitosan-based drug delivery systems,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 81, no. 3, pp. 463–469, 2012.
  12. W.-B. Chen, L.-F. Wang, J.-S. Chen, and S.-Y. Fan, “Characterization of polyelectrolyte complexes between chondroitin sulfate and chitosan in the solid state,” Journal of Biomedical Materials Research - Part A, vol. 75, no. 1, pp. 128–137, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. B. Luppi, F. Bigucci, A. Abruzzo, G. Corace, T. Cerchiara, and V. Zecchi, “Freeze-dried chitosan/pectin nasal inserts for antipsychotic drug delivery,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 75, no. 3, pp. 381–387, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. R. M. Gilhotra and D. N. Mishra, “Alginate-chitosan film for ocular drug delivery: effect of surface cross-linking on film properties and characterization,” Pharmazie, vol. 63, no. 8, pp. 576–579, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Kaur, V. Rana, S. Jain, and A. K. Tiwary, “Colon delivery of budesonide: evaluation of chitosan-chondroitin sulfate interpolymer complex,” AAPS PharmSciTech, vol. 11, no. 1, pp. 36–45, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. W. Kemp, “Infrared spectroscopy,” in Organic Spectroscopy, MacMillan, London, UK, 1991.
  17. C. Tapia, Z. Escobar, E. Costa et al., “Comparative studies on polyelectrolyte complexes and mixtures of chitosan-alginate and chitosan-carrageenan as prolonged diltiazem clorhydrate release systems,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 57, no. 1, pp. 65–75, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Jindal, V. Kumar, V. Rana, et al., “Physico-chemical, mechanical and electrical performance of bael fruit gum-chitosan IPN films,” Food Hydrocolloids, vol. 30, no. 1, pp. 192–199, 2013.
  19. G. M. Spinks, C. K. Lee, G. G. Wallace, S. I. Kim, and S. J. Kim, “Swelling behavior of chitosan hydrogels in ionic liquid-water binary systems,” Langmuir, vol. 22, no. 22, pp. 9375–9379, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. N. A. Peppas and P. A. Buri, “Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues,” Journal of Controlled Release, vol. 2, pp. 257–275, 1985. View at Scopus
  21. S.-H. S. Leung and J. R. Robinson, “The contribution of anionic polymer structural features to mucoadhesion,” Journal of Controlled Release, vol. 5, no. 3, pp. 223–231, 1988. View at Scopus
  22. K. M. Tur and H.-S. Ch'ng, “Evaluation of possible mechanism(s) of bioadhesion,” International Journal of Pharmaceutics, vol. 160, no. 1, pp. 61–74, 1998. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Wittaya-Areekul, J. Kruenate, and C. Prahsarn, “Preparation and in vitro evaluation of mucoadhesive properties of alginate/chitosan microparticles containing prednisolone,” International Journal of Pharmaceutics, vol. 312, no. 1-2, pp. 113–118, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. J. Sujja-Areevath, D. L. Munday, P. J. Cox, and K. A. Khan, “Relationship between swelling, erosion and drug release in hydrophillic natural gum mini-matrix formulations,” European Journal of Pharmaceutical Sciences, vol. 6, no. 3, pp. 207–217, 1998. View at Publisher · View at Google Scholar · View at Scopus