Identification and Characterization of DM1 Patients by a New Diagnostic Certified Assay: Neuromuscular and Cardiac Assessments

Figure 3

Expansion detection by Southern Blot Analysis. Lanes 1 and 2 are DNA Molecular Weight Marker, (VII and VIII, resp., Roche Diagnostics). Results for DM1 affected individuals are shown in lanes 3, 5, 8, and 10. Results for DM1 unaffected individuals are shown in lanes 4, 6, 7, 9, and 11, but three of these are homozygous normal (lanes 4, 7, and 9), confirmed by TP-PCR.