Microtubule-Associated Proteins in Mesial Temporal Lobe Epilepsy with and without Psychiatric Comorbidities and Their Relation with Granular Cell Layer Dispersion
Table 1
Demographic and clinical data.
MTLE
MTLE + D
MTLE + P
Controls
Statistics
Male ()
9
7
7
5
No difference
Female ()
8
10
6
5
IPI present ()
9
7
8
n.a.
No difference
IPI absent ()
8
10
5
n.a.
Age of first seizure (years)
4.2 ± 3.8
6.0 ± 6.4
6.5 ± 8.4
n.a.
No difference
Age when seizures became recurrent or age of onset (years)
10.3 ± 6.4
12.8 ± 7.9
14.6 ± 10.0
n.a.
No difference
Seizure type: CPS ()
8
3
4
n.a.
No difference
Seizure type: SGS ()
9
14
9
n.a.
Seizure frequency (monthly)
10.8 ± 10.0
15.2 ± 10.7
8.0 ± 5.4
n.a.
No difference
Right HS ()
8
8
6
n.a.
No difference
Left HS ()
8
7
5
n.a.
Bilateral HS ()
1
2
2
n.a.
Right handedness (
15
14
13
n.a.
No difference
Left handedness ()
1
2
0
n.a.
Bilateral handedness ()
1
1
0
n.a.
Memory in verbal tasks: average or above ()
5
7
2
n.a.
No difference
Memory in verbal tasks: below average ()
12
10
11
n.a.
Memory in nonverbal tasks: average or above ()
11
8
3
n.a.
Fisher’s exact test, (MTLE × MTLE + P)
Memory in nonverbal tasks: below average ()
6
9
10
n.a.
Full-scale IQ
85.7 ± 11.9
85.8 ± 8.1
77.8 ± 8.2
n.a.
No difference
Years at school
6.8 ± 3.2
6.8 ± 4.7
3.9 ± 2.5
n.a.
No difference
Age at surgery (or at death for controls, in years)
37.1 ± 6.3
37.3 ± 5.2
38.8 ± 4.3
47.3 ± 19.1
No difference
Duration of epilepsy (years)
26.7 ± 7.6
24.5 ± 9.1
24.2 ± 11.4
n.a.
No difference
Collected side: right ()
9
9
7
5
No difference
Collected side: left ()
8
8
6
5
Values indicated as mean ± std. deviation when applicable. IPI: initial precipitant injury; CPS: complex partial seizure; SGS: secondarily generalized seizures; HS: hippocampal sclerosis; n.a.: not applicable.
