Table 3: Genotype and allele frequencies of variants in the IL-1α-889 and IL-1β-511 gene, and association with ischemic stroke.

GroupsIL-1α-889 genotypeIL-1α-889 allele
TTCTCC TT versus CT + CC
, OR, 95% CI
OR, 95% CI

Control, = 48649 (10.1) 237 (48.8) 200 (41.1)637358
IS, 63 (14.3) 232 (52.7) 145 (33.0)0.0160.065
1.45, (0.97–2.15)
5223350.0061.30, (1.08–1.58)
LAA, 59 (18.4) 158 (49.4) 103 (32.2)0.001<0.05
2.01, (1.34–3.0)
3642760.0011.44, (1.18–1.78)
SVD, 4 (4.5) 44 (50.0) 40 (45.5)0.2430.098
0.42, (0.15–1.17)
124520.2040.80, (0.56–1.13)
CE, 0 (0) 16 (50.0) 16 (50.0)0.150.115
(—)
48160.1210.63, (0.36–1.13)

IL-1β-511 genotypeIL-1β-511 allele
TTCTCC TT versus CT + CC
, OR, 95% CI
OR, 95% CI

Control, 117 (24.1) 261 (53.7) 108 (22.2)477495
IS, 95 (21.6) 226 (51.3) 119 (27.1)0.2170.369
0.87, (0.63–1.18)
4644160.1160.86, (0.72–1.04)
LAA, 64 (20.0) 168 (52.5) 88 (27.5)0.1580.175
0.79, (0.56–1.11)
3442960.0660.83, (0.68–1.01)
SVD, 20 (22.7) 43 (48.9) 25 (28.4)0.4460.785
0.93, (0.54–1.6)
93830.3580.86, (0.62–1.19)
CE, 6 (18.8) 15 (46.9) 11 (34.3)0.4240.392
0.73, (0.29–1.8)
27370.2860.29, (0.80–2.20)