(a) Contrast-enhanced T1-weighted image demonstrates a necrotic glioblastoma in the right parietal lobe with increased rCBV (b) in the periphery of the tumor and peritumoral regions. (c) A single-voxel MRS, echo time 135 ms, obtained from region 1 of increased rCBV (b) shows a high Lip peak, suggesting micronecrosis. (d) MRS obtained from the region 2 of low rCBV (b) depicts an inverted Lac peak, representing hypoxia in the necrotic region.
