Table 1: Effect of BME and VTE on wound contraction, epithelization period, and scar area in excision wound.

Oral treatment
(mg/kg, od)
Wound area in mm2/rat (% contraction) Epithelization
period (days)
Scar area
(mm2)
0 day4th day8th day12th day14th day16th day18th day20th day22nd day

Control 0.5% CMC532.8 ± 6.93
(0.00)
417.7 ± 6.77
(21.6 ± 1.0)
322.3 ± 10.8
(39.5 ± 1.73)
168.5 ± 10.1
(68.3 ± 2.03)
103.3 ± 5.79
(80.6 ± 1.16)
81.2 ± 2.36
(84.8 ± 0.48)
36.2 ± 1.25
(93.2 ± 0.20)
10.3 ± 0.67
(98.1 ± 0.15)
3.17 ± 0.75
(99.4 ± 0.15)
12.7 ± 0.6799.8 ± 4.92
BME 25530.3 ± 7.15
(0.00)
359.2 ± 12.2b
(32.2 ± 2.71)
217.8 ± 20.8b
(59.0 ± 3.96)
77.2 ± 5.21c
(85.4 ± 1.08)
42.0 ± 3.86c
(92.1 ± 0.72)
22.3 ± 2.33c
(95.8 ± 0.46)
4.60 ± 0.56c
(99.0 ± 0.09)
0.0 ± 0.0c
(100.0)
0.0 ± 0.0c
(100.0)
10.3 ± 0.49a75.2 ± 4.04b
VTE 200550.0 ± 7.02
(0.00)
371.7 ± 12.1b
(32.4 ± 2.03)
229.8 ± 14.2c
(58.3 ± 2.48)
68.3 ± 2.55c
(87.6 ± 0.49)
42.8 ± 6.13c
(92.2 ± 1.12)
19.7 ± 3.02c
(96.4 ± 0.55)
3.83 ± 0.98c
(99.3 ± 0.17)
0.0 ± 0.0c
(100.0)
0.0 ± 0.0c
(100.0)
10.0 ± 0.58a74.3 ± 3.98b

Values are mean ± SEM (Percent) of 6 rats in each group. a , b , and c compared to respective day control group (statistical analysis was done by one-way analysis of variance followed by Dunnett’s test for multiple comparisons).