Table 2: Effect of BME and VTE on wet granulation tissue weight, protein, free radicals (LPO and NO), antioxidants (GSH, SOD, and CAT), and myeloperoxidase (MPO).

Oral treatment
(mg/kg, od × 10 day)
Wet tissue
mg/100 g bw
Protein
mg/g tissue
Antioxidants Free radicalsMyeloperoxidase
GSH
nM/mg protein
SOD
IU/mg protein
CAT
mU/mg protein
LPO
nM/mg protein
NO
nM/mg protein
MPO
mU/mg protein

Control 0.5% CMC359.3 ± 18.348.6 ± 2.7520.7 ± 1.170.41 ± 0.0742.9 ± 1.846.33 ± 0.5036.8 ± 4.5324.1 ± 0.55
BME 25422.7 ± 18.1a57.7 ± 2.05a24.6 ± 1.11a0.72 ± 0.02b151.6 ± 0.68c3.24 ± 0.26c15.3 ± 0.87c19.3 ± 0.29c
VTE 200461.5 ± 11.5b59.1 ± 3.40a24.5 ± 0.88a0.79 ± 0.04c210.4 ± 0.84c1.78 ± 0.15c15.2 ± 1.53b14.6 ± 0.37c

Values are mean ± SEM of 6 rats in each group. a , b , and c compared to respective control group (statistical analysis was done by one-way analysis of variance followed by Dunnett’s test for multiple comparisons).