Evaluation of In Vivo Wound Healing Activity of Bacopa monniera on Different Wound Model in Rats

Table 3

Effect of BME and VTE on dry granulation tissue, protein, hydroxyproline, hexosamine, and hexuronic acid content.

Oral treatment; (mg/kg, od × 10 day)	Dry tissue; mg/100 g bw	Protein; mg/g dry tissue	Connective tissue parameters
			Hydroxyproline; 𝜇g/mg protein	Hexosamine; 𝜇g/mg protein	Hexuronic Acid; 𝜇g/mg protein
Control 0.5% CMC	71.2 ± 3.80	244.1 ± 14.4	145.7 ± 12.6	86.6 ± 7.02	20.8 ± 3.94
BME 25	85.0 ± 3.70^a	288.4 ± 10.3^a	204.2 ± 9.44^b	122.1 ± 7.70^b	52.6 ± 2.90^c
VTE 200	92.2 ± 2.0^c	295.5 ± 17.0^a	191.1 ± 11.2^b	126.2 ± 8.97^b	46.0 ± 2.86^c

values are mean ± SEM of 6 rats in each group. ^a𝑃<0.05, ^b𝑃<0.01, and ^c𝑃<0.001 compared to respective control group (statistical analysis was done by one-way analysis of variance followed by Dunnett’s test for multiple comparisons).