Acute Toxicity and Gastroprotective Role of M. pruriens in Ethanol-Induced Gastric Mucosal Injuries in Rats

Table 1

Antioxidant activities of tissue homogenates.

Groups	NO (µM)	CAT nM/min/mL	SOD (U/g protein)	GSH (µM/mg protein)
1	9.16^*#  ±  0.04	126.66*  ±  1.86	472.58^*#  ±  4.98	16.33^*#  ±  0.07
2	9.14^*#  ±  0.18	133.68*  ±  1.90	496.20^*#  ±  4.63	15.67^*#  ±  0.19
3	3.64^#  ±  0.14	71.20^#  ±  2.88	170.43^#  ±  7.49	10.28^#  ±  0.43
4	7.65*  ±  0.20	129.83*  ±  5.13	395.14*  ±  6.03	14.48*  ±  0.13
5	5.31^*#  ±  0.10	91.18^*#  ±  3.02	300.51^*#  ±  6.49	11.51^*#  ±  0.13
6	7.19*  ±  0.03	102.35^*#  ±  3.38	348.12^*#  ±  4.75	11.95^*#  ±  0.21
7	7.06^*#  ±  0.11	109.61^*#  ±  5.02	367.81^*#  ±  4.30	13.17^*#  ±  0.13
8	6.15^*#  ±  0.03	133.71*  ±  1.56	387.37*  ±  3.34	13.27^*#  ±  0.23

NO: nitric oxide; SOD: superoxide dismutase; GSH: glutathione. Groups 1 to 4 represent the negative control group, the extract control group, the ulcer control group, and the reference control group, respectively. The experimental groups are presented as groups 4–8. All values are expressed as mean  ±  standard error mean. Mean difference is significant at the 𝑃<0.05 level (one-way between groups ANOVA with post hoc analysis). ∗Significant when compared with the group 3. #Significant when compared with the group 4.