Research Article

Loss of RASSF1A Expression in Colorectal Cancer and Its Association with K-ras Status

Table 2

Association between loss of RASSF1A expression and clinicopathological factors.

FactorsTotal casesLoss of RASSF1A expression
No. No. (% of total) P

Age
 <604122 (53.66%)0.1960.658
 ≥603517 (48.57%)
Sex
 Male4427 (61.36%)4.2230.040
 Female3212 (37.5%)
Site
 Colon3824 (63.16%)4.2660.039
 Rectum3815 (39.47%)
Tumor size
 <5 cm5531 (56.36%)2.0300.154
 ≥5 cm218 (38.10%)
Differentiation grade
 Poor3213 (40.63%)2.5290.112
 Moderate-well4426 (59.09%)
Invasion depth
 T1 + T21711 (64.71%)1.5720.210
 T3 + T45928 (47.58%)
Tumor stage
 I/II/III5628 (50%)0.1140.736
 IV2011 (55%)

Bold values represent values which are considered to be statistically significant at 0.05.