Research Article
Loss of RASSF1A Expression in Colorectal Cancer and Its Association with K-ras Status
Table 3
Relationship between loss of RASSF1A expression, K-ras mutation, and EGFR status in CRC.
| | RASSF1A expression | | | | Negative | Positive |
| K-ras status | | | | | Wild-type | 30 (40%) | 18 (24%) | | | Mutated | 9 (11%) | 19 (25%) | 6.523 | 0.011 |
EGFR expression | | | | | Low | 30 (39%) | 32 (42%) | | | High | 9 (12%) | 5 (7%) | 0.018 | 0.895 |
| | K-ras status | | | | Wild-type | Mutated | | |
| EGFR expression | | | | | Low | 40 (52%) | 22 (29%) | | | High | 8 (11%) | 6 (8%) | 0.267 | 0.605 |
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Bold values represent values which are considered to be statistically significant at 0.05.
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