Research Article

Loss of RASSF1A Expression in Colorectal Cancer and Its Association with K-ras Status

Table 3

Relationship between loss of RASSF1A expression, K-ras mutation, and EGFR status in CRC.

RASSF1A expression
NegativePositive

K-ras status
 Wild-type30 (40%)18 (24%)
 Mutated9 (11%)19 (25%)6.5230.011
EGFR expression
 Low30 (39%)32 (42%)
 High9 (12%)5 (7%) 0.0180.895

K-ras status
Wild-typeMutated

EGFR expression
 Low40 (52%)22 (29%)
 High8 (11%)6 (8%)0.2670.605

Bold values represent values which are considered to be statistically significant at 0.05.