Research Article
Single Nucleotide Polymorphism in the Promoter of the Human Interleukin-13 Gene Is Associated with Asthma in Malaysian Adults
Table 2
The (a) genotype and (b) allele frequencies for asthmatic patients and control subjects of SNP in the human IL-13 gene.
(a) |
| Site | Genotype | Frequencies | valuea | DFb | Asthmatic patients () | Control subjects () |
| | CC | 20 (2.3%) | 41 (43.6%) | | | −1111C>T | CT | 51 (58.6%) | 43 (45.7%) | 0.011 | 2 | | TT | 16 (18.4%) | 10 (10.6%) | | |
| | GG | 28 (32.2%) | 24 (25.5%) | | | 4257G>A | GA | 39 (44.8%) | 57 (60.6%) | 0.086 | 2 | | AA | 20 (23.0%) | 13 (13.8%) | | |
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(b) |
| Site | Genotype | Frequencies | valuea | DFb | Asthmatic patients () | Normal subjects () |
| −1111C>T | C | 91 (52.3%) | 125 (66.5%) | 0.006 | 1 | T | 83 (47.7%) | 63 (33.5%) |
| 4257G>A | G | 95 (54.6%) | 105 (55.9%) | 0.811 | 1 | A | 79 (45.4%) | 83 (44.1%) |
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Chi-square test.
bDF: degree of freedom.
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