Single Nucleotide Polymorphism in the Promoter of the Human Interleukin-13 Gene Is Associated with Asthma in Malaysian Adults

Table 2

The (a) genotype and (b) allele frequencies for asthmatic patients and control subjects of SNP in the human IL-13 gene.

(a)  

Site	Genotype	Frequencies		𝑃 value^a	DF^b
		Asthmatic patients (𝑛=87)	Control subjects (𝑛=94)
	CC	20 (2.3%)	41 (43.6%)
−1111C>T	CT	51 (58.6%)	43 (45.7%)	0.011	2
	TT	16 (18.4%)	10 (10.6%)
	GG	28 (32.2%)	24 (25.5%)
4257G>A	GA	39 (44.8%)	57 (60.6%)	0.086	2
	AA	20 (23.0%)	13 (13.8%)

(b)  

Site	Genotype	Frequencies		𝑃 value^a	DF^b
		Asthmatic patients (𝑛=87)	Normal subjects (𝑛=94)
−1111C>T	C	91 (52.3%)	125 (66.5%)	0.006	1
	T	83 (47.7%)	63 (33.5%)
4257G>A	G	95 (54.6%)	105 (55.9%)	0.811	1
	A	79 (45.4%)	83 (44.1%)

aChi-square test.
^bDF: degree of freedom.