Neuroprotective Activity of Thioctic Acid in Central Nervous System Lesions Consequent to Peripheral Nerve Injury
Figure 5
High magnification of the sections of the sensory cortex (S1HL) processed for the immunohistochemical demonstration of glial fibrillary acidic protein (GFAP). (a) Control Sham-operated WKY rats, (b) control Sham-operated SHRs, (c) control CCI SHRs, (d) CCI SHRs treated with ()-thioctic acid 250 μmol/kg/day, (e) CCI SHRs treated with ()-thioctic acid 125 μmol/kg/day, (f) CCI SHRs treated with (+)-thioctic acid 125 μmol/kg/day, (g) CCI SHRs treated with (−)-thioctic acid 125 μmol/kg/day, and (h) CCI SHRs treated with pregabalin 300 μmol/kg/day (H). II: zone 2 of sensory cortex. Calibration bar: 25 μm.
