Neuroprotective Activity of Thioctic Acid in Central Nervous System Lesions Consequent to Peripheral Nerve Injury

Table 1

Systolic blood pressure values.

	Treatment	Before Treatment		After Treatment
		WKY	SHR	WKY	SHR
Sham	Vehicle	156±7	209±6^∗	144±9	213±3^∗
CCI	Vehicle	145±6	220±8^∗	149±13	232±16^∗
CCI	(+/−)-Thioctic acid 250 𝜇mol/Kg/day	157±9	198±8^∗	155±8	207±5^∗
CCI	(+/−)-Thioctic acid 125 𝜇mol/Kg/day	149±11	208±12^∗	150±14	205±9^∗
CCI	(+)-Thioctic acid 125 𝜇mol/Kg/day	148±6	211±11^∗	136±13	225±8^∗
CCI	(−)-Thioctic acid 125 𝜇mol/Kg/day	154±4	201±14^∗	156±9	217±9^∗
CCI	Pregabalin 300 𝜇mol/Kg/day	150±6	215±5^∗	146±5	201±9^∗

The data are expressed as mmHg and are the mean of 3 different measurements. ^∗𝑃<0.01 versus WKY rats of the same group of treatment.