Research Article

Comparative Analysis of Context-Dependent Mutagenesis Using Human and Mouse Models

Table 1

The fractions of basic types of directed mutations, inferred from SNP data.

MutationFraction
H. sapiens M. musculus

A > T 0.0310.034
T > A0.0310.034
A > C0.0370.029
T > G0.0380.029
C > G0.0510.035
G > C0.0510.035
G > T0.0580.059
C > A0.0580.059
T > C0.1180.097
A > G0.1180.097
C > T0.2040.247
G > A0.2040.247
Transversions0.3550.312
Transitions0.6450.688