Research Article

Emodin Augments Cisplatin Cytotoxicity in Platinum-Resistant Ovarian Cancer Cells via ROS-Dependent MRP1 Downregulation

Figure 2

Effect of emodin on cDDP-induced apoptosis in cDDP-resistant COC1/DDP cells. (a) Representative density plots of flow cytometric analysis on the fraction of apoptotic cells 24 h after the indicated treatments detected with annexin V/propidium iodide. (b) The histogram represents the mean values of three independent experiments. versus cDDP-only treated cells; versus the 30 μM DDP + 50 μM emodin cotreated cells.
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