Altered Pulmonary Lymphatic Development in Infants with Chronic Lung Disease
Figure 4
Percent parenchyma and interstitium podoplanin stained (representing lymphatic tissue) at the respiratory bronchiolar and alveolar ductal levels in infants with CLD versus controls. (a) and (b) include CLD infants from both pre- and postsurfactant eras; (c) and (d) include infants from postsurfactant era only. Podoplanin staining is consistently increased at both levels in infants with CLD reaching statistical significance at the alveolar ductal level with percent parenchyma stained ((a) and (c)).
