Endothelial Function in a Mouse Model of Myeloperoxidase Deficiency

Table 2

General data for carotid arteries in experimental groups.

Carotid arteries	MPO^−/−		Wild-type
	Control	LPS-treated	Control	LPS-treated
	M ± SEM; mN/mm	M ± SEM; mN/mm	M ± SEM; mN/mm	M ± SEM; mN/mm
Contraction (tension)
1 𝜇M PE	1.31 ± 0.21; 𝑛=5	1.46 ± 0.08; 𝑛=8	1.51 ± 0.06; 𝑛=4	1.52 ± 0.09; 𝑛=8
1 𝜇M PE after L-NAME	1.43 ± 0.10; 𝑛=5	1.37 ± 0.04; 𝑛=2	1.56 ± 0.13; 𝑛=4	1.64 ± 0.15; 𝑛=2
3 𝜇M PE	0.90 ± 0.11; 𝑛=10	1.13 ± 0.06; 𝑛=10	1.03 ± 0.07; 𝑛=8	1.21 ± 0.06; 𝑛=10
3 𝜇M PE in high K^+	1.44 ± 0.11; 𝑛=10	1.56 ± 0.06; 𝑛=10	1.54 ± 0.11; 𝑛=8	1.72 ± 0.11; 𝑛=10
High K^+	1.22 ± 0.13; 𝑛=10	1.41 ± 0.09; 𝑛=10	1.27 ± 0.11; 𝑛=8	1.40 ± 0.09; 𝑛=10
Relaxation (% of change in tension)
Maximal relaxation to acetylcholine	92.20 ± 1.15; 𝑛=5	93.86 ± 3.88; 𝑛=8	94.24 ± 1.36; 𝑛=4	94.90 ± 1.65; 𝑛=8