Endothelial Function in a Mouse Model of Myeloperoxidase Deficiency

Table 3

General data for saphenous arteries in experimental groups.

Saphenous arteries	MPO^−/−	Wild-type
	Control	Control
	M ± SEM; mN/mm	M ± SEM; mN/mm
Contraction (tension)
1 𝜇M PE	2.69 ± 0.41; 𝑛=5	2.68 ± 0.40; 𝑛=5
1 𝜇M PE after L-NAME	2.91 ± 0.15**; 𝑛=5	3.59 ± 0.11; 𝑛=5
3 𝜇M PE	2.90 ± 0.20; 𝑛=10	3.12 ± 0.17; 𝑛=10
3 𝜇M PE in high K^+	3.61 ± 0.21**; 𝑛=10	4.36 ± 0.09; 𝑛=10
High K^+	3.36 ± 0.21**; 𝑛=10	4.03 ± 0.08; 𝑛=10
Relaxation (% of change in tension)
Maximal relaxation to acetylcholine	99.07 ± 0.81; 𝑛=5	99.89 ± 0.12; 𝑛=5
Maximal relaxation to acetylcholine after L-NAME	94.37 ± 1.60; 𝑛=5	97.08 ± 0.50; 𝑛=5

^∗∗𝑃<0.01.