Essential Functional Modules for Pathogenic and Defensive Mechanisms in Candida albicans Infections

Table 1

Enriched functional modules for pathogenic mechanisms in C. albicans and the corresponding significant proteins shown in Figure 2 during the host-pathogen interaction.

Functional module	Protein symbol
Hyphal morphogenesis	Cas4, Als3, Ifd6, Kis1, Mac4, Ndt80, orf19.6705
Ion and small molecule transport	Tna1, Agp2, Can1, Mac1, Als3, orf19.3769, Git1, Hut1, Mcd4, Mep1, Mrs7, orf19.1403, orf19.1427, orf19.2322.3, orf19.3132, orf19.3558, orf19.4897, Seo1, Sfc1, Vcx1
Protein secretion	Sap4, Sap5, Sap6, Sro77, Sys3, Ddi1, orf19.3247, orf19.7261, orf19.7604, orf19.841, Plb2, Prd1, Sec20, Spc3
Shifts in carbon utilization	Lat1, orf19.3782, Tes15, orf19.4121, Tes1, Pyc2, Acc1, Agp2, Pox1-3

This table lists four of the functional modules considered to be significant in C. albicans pathogenesis and the corresponding proteins with associated GO annotation.