Negative Regulation of GADD34 on Myofibroblasts during Cutaneous Wound Healing
Figure 3
Enhanced expression of collagen protein during wound healing in GADD34 −/− mice. (a) Relative expression of Col1α1 and Col3α1 in granulation tissues of WT and GADD34−/− mice from 0 to 16 days after wounding was analyzed by real-time PCR. All results were normalized to β-actin values. All experiments were done in triplicate and data presented as means ± SD. (b) Frozen sections from tissues at 6 days after wounding were subjected to Masson trichrome staining. (c) Blue-positive area was calculated from 5 sections using Image J software and data presented as means ± SEM. . , .
