Research Article
In Silico Investigation of Potential mTOR Inhibitors from Traditional Chinese Medicine for Treatment of Leigh Syndrome
Table 1
Scoring functions of top candidates and Torin2 from TCM database screening.
| | Name | Resource | -PLP1 | -PLP2 | Dock Score |
| | Picrasidine M | Picrasma quassioides (D. Don) Benn. | 118.22 | 104.11 | 88.913 | | Acerosin | Vitex negundo L. | 104.12 | 108.76 | 78.088 | | Psychotrine | Alangium lamarckii | 107.12 | 97.2 | 75.322 | | 3,5,6-Trihydroxy-3',4',7-trimethoxyflavone | Citrus medica L. var. sarcodactylis (Noot.) Swingie | 106.07 | 105.45 | 73.906 | | Torin | | 115.23 | 107.26 | 55.507 |
|
|
Control.
|
