Research Article

Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer

Figure 2

Number of samples with the various types of data. Information for DNA sequence mutation (green, ), copy-number (purple, ), and methylation (orange, ) were retrieved from the cBio portal for Cancer Genomics. For subsequent frequency calculations comparing genetic and epigenetic mechanisms, we focused on the cases with both copy-number and methylation data ( , i.e., cases circled in red).
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