Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer

<table><i>DNA-level alteration affecting components of the KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in OVCA tumors</i>. Alteration status of individual complex component genes (<i>KEAP1</i> in blue,<i> CUL3</i> in green, and<i> RBX1</i> in yellow) across a panel of 588 ovarian tumors is indicated by colored boxes.</table>

BioMed Research International

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Figure 3

Figure 3: Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer 