Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer

<table><i>Loss of function alterations affecting each complex component gene</i>. The frequency of DNA sequence mutations (black), DNA copy-number loss (CNL, dark grey), and promoter methylation (light grey) affecting each complex gene is shown.</table>

BioMed Research International

fig4

Figure 4

Figure 4: Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer 