Individual Osmotic Fragility Distribution: A New Parameter for Determination of the Osmotic Properties of Human Red Blood Cells

Figure 3

Haemolysis for control and ozone treated human erythrocytes. The upper right figure shows the distribution of osmotic properties calculated from the first derivative of the haemolysis curve. The mean osmotic fragility increases, and the osmotic properties are much more widely dispersed in comparison to the control samples. A nonzero value of the distribution function for the isotonic solution is a consequence of spontaneous haemolysis of cells in the isotonic solution.